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Dr Russ Blog - Grapefruit is Great - But Maybe Not With Your Medications
Grapefruit is Great - But Maybe Not With Your Medications
Created on 1/14/2011

G sent in a very good question - he is taking medication and the instructions say he should not to take it with grapefruit - he wonders if he can take the medication at night and safely have his grapefruit in the morning?

The short answer, G, is probably not.

Grapefruit contains compounds that interefere with enzymes that break down, or metabolize, some medications. If these enzymes are not metabolized normally the drug concentrations in your body can remain high for too long, placing your health at risk.

This interaction between grapefruit and medication is not present with every medicine, only some of them; however, the interaction is an issue with some of the most commonly used pharmaceuticals such as statin drugs, antihistamines, calcium channel blockers and immunosuppressants.

The extent of the interaction depends on a number of factors, including the specific medication involved and a given person's unique biochemistry; however, even a small amount of grapefruit or grapefruit juice can impact drug levels in your body.

And speaking to your question specifically, G, the effects can last for 1-3 days.

in your circumstance most experts would recommend asking your doctor if there is a similar medication you can take that is not affected by grapefruit or grapefruit juice. Short of that, switching to another beverage or fruit might be best.

I wish I had better news for you, G, but I hope this information is helpful to you.

Be well.
Dr. Russ
** Information on this web site is provided for informational purposes only and is not intended as a substitute for the advice provided by your physician or other healthcare professional. You should not use the information on this web site for diagnosing or treating a health problem or disease, or prescribing any medication or other treatment. **

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